Original Research Article
The neuroterrain 3D mouse brain atlas
Department of Neurobiology & Anatomy, Drexel University College of Medicine, USA
A significant objective of neuroinformatics is the construction of tools to readily access, search, and analyze ana-tomical imagery. This goal can be subdivided into development of the necessary databases and of the computer vision tools for image analysis. When considering mesoscale images, the latter tools can be further divided into registration algorithms and anatomical models. The models are atlases that contain both bitmap images and tem-plates of anatomical boundaries. We report here on construction of such a model for the C57BL/6J mouse. The intended purpose of this atlas is to aid in automated delineation of the Mouse Brain Library, a database of brain his-tological images of importance to neurogenetic research.
Keywords: atlas, 3D reconstruction, brain model, automated segmentation, neuroanatomy, spatial normalization, standard coordinate space, registration
Copyright: © 2008 Bertrand and Nissanov. This is an open-access article subject to an exclusive license agreement between the authors and the Frontiers Research Foundation, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited.
*Correspondence: Jonathan Nissanov, Department of Neurobiology & Anatomy, Drexel University College of Medicine, 2900 Queen Lane, Philadelphia, PA 19129, USA. e-mail: jonathan.nissanov@drexelmed.edu
Citation: Bertrand L and Nissanov J (2008) The neuroterrain 3D mouse brain atlas. Front. Neuroinform. (2008) 2:3. doi:10.3389/neuro.11.003.2008
Received: 05 March 2008; paper pending published: 17 April 2008; accepted: 10 July 2008; published online: 19 July 2008.
Edited by:
Maryann E. Martone, University of California San Diego, USA
Reviewed by:
Richard A. Baldock, Medical Ressearch Council Human Genetics Unit, UK
Gully A. Burns, USC Information Sciences Institute, USA
Gully A. Burns, USC Information Sciences Institute, USA
*Correspondence: Jonathan Nissanov, Department of Neurobiology & Anatomy, Drexel University College of Medicine, 2900 Queen Lane, Philadelphia, PA 19129, USA. e-mail: jonathan.nissanov@drexelmed.edu
